| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 30-10-10 17:00 | FC Valencia | Real Zaragoza | 1:1 |
| 30-10-10 19:00 | Hercules Alicante | Real Madrid | 1:3 |
| 30-10-10 21:00 | FC Barcelona | FC Sevilla | 5:0 |
| 31-10-10 16:00 | Sporting Gijón | FC Villarreal | 1:1 |
| 31-10-10 16:00 | Racing Santander | CA Osasuna | 4:1 |
| 31-10-10 16:00 | FC Málaga | Real Sociedad | 1:2 |
| 31-10-10 16:00 | Deportivo La Coruña | Espanyol Barcelona | 3:0 |
| 31-10-10 18:00 | Atlético Madrid | UD Almeria | 1:1 |
| 31-10-10 20:00 | Athletic Bilbao | FC Getafe | 3:0 |
| 01-11-10 20:00 | RCD Mallorca | UD Levante | 2:1 |