| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 21-05-21 20:00 | UD Levante | FC Cádiz | 2:2 |
| 22-05-21 17:00 | Real Valladolid | Atlético Madrid | 1:2 |
| 22-05-21 17:00 | Real Madrid | FC Villarreal | 2:1 |
| 22-05-21 17:00 | SD Huesca | FC Valencia | 0:0 |
| 22-05-21 17:00 | CA Osasuna | Real Sociedad | 0:1 |
| 22-05-21 17:00 | Celta Vigo | Real Betis Sevilla | 2:3 |
| 22-05-21 17:00 | FC Elche | Athletic Bilbao | 2:0 |
| 22-05-21 17:00 | SD Eibar | FC Barcelona | 0:1 |
| 23-05-21 17:30 | FC Granada | FC Getafe | 0:0 |
| 23-05-21 20:00 | FC Sevilla | Deportivo Alavés | 1:0 |