| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 23-10-10 17:00 | Real Zaragoza | FC Barcelona | 0:2 |
| 23-10-10 19:00 | Real Madrid | Racing Santander | 6:1 |
| 23-10-10 21:00 | FC Valencia | RCD Mallorca | 1:2 |
| 24-10-10 16:00 | FC Getafe | Sporting Gijón | 3:0 |
| 24-10-10 16:00 | UD Almeria | Hercules Alicante | 1:1 |
| 24-10-10 16:00 | CA Osasuna | FC Málaga | 3:0 |
| 24-10-10 16:00 | Espanyol Barcelona | UD Levante | 2:1 |
| 24-10-10 18:00 | FC Sevilla | Athletic Bilbao | 4:3 |
| 24-10-10 20:00 | FC Villarreal | Atlético Madrid | 2:0 |
| 25-10-10 20:00 | Real Sociedad | Deportivo La Coruña | 3:0 |