| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 25-09-10 17:00 | Sporting Gijón | FC Valencia | 0:2 |
| 25-09-10 19:00 | UD Levante | Real Madrid | 0:0 |
| 25-09-10 21:00 | Athletic Bilbao | FC Barcelona | 1:3 |
| 26-09-10 16:00 | Racing Santander | FC Getafe | 0:1 |
| 26-09-10 16:00 | Deportivo La Coruña | UD Almeria | 0:2 |
| 26-09-10 16:00 | Espanyol Barcelona | CA Osasuna | 1:0 |
| 26-09-10 16:00 | RCD Mallorca | Real Sociedad | 2:0 |
| 26-09-10 18:00 | Hercules Alicante | FC Sevilla | 2:0 |
| 26-09-10 20:00 | Atlético Madrid | Real Zaragoza | 1:0 |
| 27-09-10 20:00 | FC Málaga | FC Villarreal | 2:3 |