| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 21-09-10 19:00 | CA Osasuna | Real Sociedad | 3:1 |
| 21-09-10 19:00 | Athletic Bilbao | RCD Mallorca | 3:0 |
| 21-09-10 21:00 | Real Madrid | Espanyol Barcelona | 3:0 |
| 22-09-10 19:00 | FC Barcelona | Sporting Gijón | 1:0 |
| 22-09-10 19:00 | Real Zaragoza | Hercules Alicante | 0:0 |
| 22-09-10 19:00 | UD Almeria | UD Levante | 0:1 |
| 22-09-10 21:00 | FC Valencia | Atlético Madrid | 1:1 |
| 23-09-10 19:00 | FC Getafe | FC Málaga | 0:2 |
| 23-09-10 19:00 | FC Villarreal | Deportivo La Coruña | 1:0 |
| 23-09-10 21:00 | FC Sevilla | Racing Santander | 1:1 |