| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 04-12-10 17:00 | UD Levante | Atlético Madrid | 2:0 |
| 04-12-10 19:45 | CA Osasuna | FC Barcelona | 0:3 |
| 04-12-10 21:00 | Real Madrid | FC Valencia | 2:0 |
| 05-12-10 16:00 | FC Getafe | RCD Mallorca | 3:0 |
| 05-12-10 16:00 | UD Almeria | Real Zaragoza | 1:1 |
| 05-12-10 16:00 | Espanyol Barcelona | Sporting Gijón | 1:0 |
| 05-12-10 16:00 | FC Málaga | Racing Santander | 4:1 |
| 05-12-10 18:00 | FC Villarreal | FC Sevilla | 1:0 |
| 05-12-10 20:00 | Real Sociedad | Athletic Bilbao | 2:0 |
| 06-12-10 20:00 | Deportivo La Coruña | Hercules Alicante | 1:0 |