| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 27-11-10 17:00 | Real Zaragoza | FC Villarreal | 0:3 |
| 27-11-10 19:00 | FC Sevilla | FC Getafe | 1:3 |
| 27-11-10 21:00 | Atlético Madrid | Espanyol Barcelona | 2:3 |
| 28-11-10 16:00 | Sporting Gijón | Real Sociedad | 1:3 |
| 28-11-10 16:00 | Hercules Alicante | UD Levante | 3:1 |
| 28-11-10 16:00 | Racing Santander | Deportivo La Coruña | 1:0 |
| 28-11-10 16:00 | RCD Mallorca | FC Málaga | 2:0 |
| 28-11-10 18:00 | Athletic Bilbao | CA Osasuna | 1:0 |
| 28-11-10 20:00 | FC Valencia | UD Almeria | 2:1 |
| 29-11-10 20:00 | FC Barcelona | Real Madrid | 5:0 |