| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 20-11-10 17:00 | FC Villarreal | FC Valencia | 1:1 |
| 20-11-10 19:00 | UD Almeria | FC Barcelona | 0:8 |
| 20-11-10 21:00 | Real Madrid | Athletic Bilbao | 5:1 |
| 21-11-10 16:00 | CA Osasuna | Sporting Gijón | 1:0 |
| 21-11-10 16:00 | Espanyol Barcelona | Hercules Alicante | 3:0 |
| 21-11-10 16:00 | UD Levante | Racing Santander | 3:1 |
| 21-11-10 16:00 | Deportivo La Coruña | FC Málaga | 3:0 |
| 21-11-10 18:00 | FC Sevilla | RCD Mallorca | 1:2 |
| 21-11-10 20:00 | Real Sociedad | Atlético Madrid | 2:4 |
| 22-11-10 20:00 | FC Getafe | Real Zaragoza | 1:1 |