| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 14-05-22 14:30 | VfB Estugarda | 1. FC Colónia | 2:1 |
| 14-05-22 14:30 | Bor. Mönchengladbach | 1899 Hoffenheim | 5:1 |
| 14-05-22 14:30 | 1. FC Union Berlim | VfL Bochum | 3:2 |
| 14-05-22 14:30 | Bayer 04 Leverkusen | SC Friburgo | 2:1 |
| 14-05-22 14:30 | Borussia Dortmund | Hertha BSC Berlim | 2:1 |
| 14-05-22 14:30 | Arminia Bielefeld | RB Leipzig | 1:1 |
| 14-05-22 14:30 | FC Augsburg | SpVgg Greuther Fürth | 2:1 |
| 14-05-22 14:30 | FSV Mainz 05 | Eintracht Frankfurt | 2:2 |
| 14-05-22 14:35 | VfL Wolfsburgo | FC Bayern Munique | 2:2 |