| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 24-10-20 17:15 | FC Cartagena | UD Las Palmas | 3:0 |
| 24-10-20 17:15 | UD Logroñés | CD Lugo | 2:3 |
| 24-10-20 19:30 | UD Almeria | CF Fuenlabrada | 3:0 |
| 24-10-20 19:30 | CD Castellón | FC Girona | 0:1 |
| 25-10-20 15:00 | Sporting Gijón | SD Ponferradina | 2:1 |
| 25-10-20 17:15 | CD Teneriffa | Espanyol Barcelona | 0:0 |
| 25-10-20 17:15 | CD Leganés | Real Oviedo | 2:1 |
| 25-10-20 19:30 | FC Málaga | CD Mirandés | 1:1 |
| 25-10-20 19:30 | Albacete Balompie | Rayo Vallecano | 2:1 |
| 25-10-20 20:00 | Real Zaragoza | CD Sabadell | 0:0 |
| 26-10-20 17:00 | AD Alcorcón | RCD Mallorca | 0:2 |