| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 21-10-20 15:30 | Espanyol Barcelona | CD Mirandés | 2:0 |
| 21-10-20 18:00 | CD Lugo | FC Girona | 3:0 |
| 21-10-20 18:00 | UD Las Palmas | CD Castellón | 2:1 |
| 21-10-20 18:00 | SD Ponferradina | CD Teneriffa | 1:0 |
| 21-10-20 20:30 | CF Fuenlabrada | UD Logroñés | 0:0 |
| 21-10-20 20:30 | UD Almeria | FC Cartagena | 1:1 |
| 22-10-20 15:30 | CD Leganés | Real Zaragoza | 1:0 |
| 22-10-20 18:00 | Real Oviedo | Rayo Vallecano | 0:0 |
| 22-10-20 18:00 | RCD Mallorca | Albacete Balompie | 0:0 |
| 22-10-20 20:30 | FC Málaga | Sporting Gijón | 1:0 |
| 09-12-20 18:00 | CD Sabadell | AD Alcorcón | 1:1 |