| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 03-10-20 15:00 | AD Alcorcón | Real Zaragoza | 0:3 |
| 03-10-20 15:00 | CD Mirandés | SD Ponferradina | 0:1 |
| 03-10-20 17:15 | Albacete Balompie | Real Oviedo | 1:1 |
| 03-10-20 17:15 | RCD Mallorca | CD Teneriffa | 2:0 |
| 03-10-20 19:30 | UD Las Palmas | UD Logroñés | 2:1 |
| 03-10-20 20:00 | Rayo Vallecano | FC Málaga | 4:0 |
| 04-10-20 11:00 | FC Girona | CF Fuenlabrada | 0:1 |
| 04-10-20 15:00 | CD Sabadell | Espanyol Barcelona | 0:1 |
| 04-10-20 17:15 | CD Castellón | CD Leganés | 2:0 |
| 04-10-20 17:15 | UD Almeria | Sporting Gijón | 0:1 |
| 04-10-20 19:30 | FC Cartagena | CD Lugo | 2:1 |