| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 26-03-21 18:00 | Sporting Gijón | AD Alcorcón | 0:0 |
| 26-03-21 20:00 | CD Castellón | Espanyol Barcelona | 1:3 |
| 27-03-21 15:00 | Real Oviedo | SD Ponferradina | 1:1 |
| 27-03-21 17:15 | UD Almeria | CD Leganés | 1:1 |
| 27-03-21 19:30 | FC Cartagena | FC Málaga | 1:1 |
| 27-03-21 20:00 | UD Logroñés | Real Zaragoza | 1:1 |
| 28-03-21 13:00 | CD Lugo | CD Sabadell | 0:1 |
| 28-03-21 15:00 | FC Girona | Albacete Balompie | 2:1 |
| 28-03-21 20:30 | CD Teneriffa | UD Las Palmas | 1:1 |
| 29-03-21 20:00 | CF Fuenlabrada | RCD Mallorca | 4:1 |
| 14-04-21 18:00 | Rayo Vallecano | CD Mirandés | 0:1 |