| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 26-09-20 15:00 | Real Zaragoza | UD Las Palmas | 2:2 |
| 26-09-20 17:15 | Sporting Gijón | FC Girona | 2:0 |
| 26-09-20 17:15 | FC Málaga | AD Alcorcón | 1:0 |
| 26-09-20 17:15 | UD Logroñés | CD Castellón | 1:1 |
| 26-09-20 19:30 | CF Fuenlabrada | Albacete Balompie | 1:0 |
| 27-09-20 11:00 | CD Lugo | UD Almeria | 0:2 |
| 27-09-20 15:00 | RCD Mallorca | CD Sabadell | 1:0 |
| 27-09-20 17:15 | CD Teneriffa | CD Mirandés | 1:2 |
| 27-09-20 17:15 | Real Oviedo | Espanyol Barcelona | 0:2 |
| 27-09-20 17:15 | SD Ponferradina | Rayo Vallecano | 3:0 |
| 27-09-20 19:30 | CD Leganés | FC Cartagena | 3:1 |