| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 26-02-21 18:00 | CD Sabadell | Albacete Balompie | 0:0 |
| 26-02-21 20:00 | FC Cartagena | CD Leganés | 1:0 |
| 27-02-21 15:00 | Rayo Vallecano | SD Ponferradina | 1:1 |
| 27-02-21 17:15 | UD Almeria | CD Lugo | 4:1 |
| 27-02-21 19:30 | CD Castellón | UD Las Palmas | 4:0 |
| 27-02-21 20:00 | UD Logroñés | RCD Mallorca | 0:1 |
| 28-02-21 13:00 | CF Fuenlabrada | FC Girona | 1:1 |
| 28-02-21 15:00 | Sporting Gijón | Espanyol Barcelona | 1:1 |
| 28-02-21 17:15 | CD Teneriffa | AD Alcorcón | 3:1 |
| 28-02-21 20:00 | Real Oviedo | Real Zaragoza | 1:0 |
| 01-03-21 18:00 | CD Mirandés | FC Málaga | 1:0 |