| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 20-11-20 18:00 | AD Alcorcón | CD Lugo | 1:0 |
| 20-11-20 20:00 | Espanyol Barcelona | FC Girona | 1:2 |
| 21-11-20 13:00 | FC Málaga | CD Leganés | 1:2 |
| 21-11-20 15:00 | CD Mirandés | FC Cartagena | 4:1 |
| 21-11-20 17:15 | Rayo Vallecano | CD Castellón | 2:1 |
| 21-11-20 19:30 | Real Oviedo | CF Fuenlabrada | 1:1 |
| 22-11-20 13:00 | CD Sabadell | UD Las Palmas | 3:1 |
| 22-11-20 15:00 | RCD Mallorca | Sporting Gijón | 0:0 |
| 22-11-20 17:15 | CD Teneriffa | UD Logroñés | 0:1 |
| 22-11-20 20:00 | SD Ponferradina | Real Zaragoza | 2:1 |
| 23-11-20 20:00 | Albacete Balompie | UD Almeria | 1:2 |