| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 27-08-22 1:00 | Puebla FC | FC Juarez | 2:2 |
| 27-08-22 3:05 | Mazatlán FC | CF America | 1:3 |
| 27-08-22 23:00 | CD Cruz Azul | Queretaro F.C. | 2:1 |
| 28-08-22 1:05 | Tigres de UANL | CID Necaxa | 0:0 |
| 28-08-22 3:05 | Deportivo Guadalajara | UNAM Pumas | 3:1 |
| 28-08-22 18:00 | Deportivo Toluca | CF Pachuca | 1:4 |
| 29-08-22 1:00 | Club Leon | Atlas Guadalajara | 4:2 |
| 29-08-22 1:05 | Santos Laguna | San Luis | 4:1 |
| 29-08-22 3:05 | Club Tijuana | CF Monterrey | 0:3 |