| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 23-10-10 12:45 | Tottenham Hotspurs | FC Everton | 1:1 |
| 23-10-10 15:00 | Birmingham City | FC Blackpool | 2:0 |
| 23-10-10 15:00 | FC Chelsea | Wolverhampton Wanderers | 2:0 |
| 23-10-10 15:00 | AFC Sunderland | Aston Villa | 1:0 |
| 23-10-10 15:00 | West Bromwich Albion | FC Fulham | 2:1 |
| 23-10-10 15:00 | Wigan Athletic | Bolton Wanderers | 1:1 |
| 23-10-10 17:30 | West Ham United | Newcastle United | 1:2 |
| 24-10-10 13:30 | FC Stoke City | Manchester United | 1:2 |
| 24-10-10 15:00 | FC Liverpool | Blackburn Rovers | 2:1 |
| 24-10-10 16:00 | Manchester City | FC Arsenal | 0:3 |