| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 16-10-10 15:00 | FC Arsenal | Birmingham City | 2:1 |
| 16-10-10 15:00 | Bolton Wanderers | FC Stoke City | 2:1 |
| 16-10-10 15:00 | FC Fulham | Tottenham Hotspurs | 1:2 |
| 16-10-10 15:00 | Manchester United | West Bromwich Albion | 2:2 |
| 16-10-10 15:00 | Newcastle United | Wigan Athletic | 2:2 |
| 16-10-10 15:00 | Wolverhampton Wanderers | West Ham United | 1:1 |
| 16-10-10 17:30 | Aston Villa | FC Chelsea | 0:0 |
| 17-10-10 13:30 | FC Everton | FC Liverpool | 2:0 |
| 17-10-10 16:00 | FC Blackpool | Manchester City | 2:3 |
| 18-10-10 20:00 | Blackburn Rovers | AFC Sunderland | 0:0 |