| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 11-09-10 12:45 | FC Everton | Manchester United | 3:3 |
| 11-09-10 15:00 | FC Arsenal | Bolton Wanderers | 4:1 |
| 11-09-10 15:00 | FC Fulham | Wolverhampton Wanderers | 2:1 |
| 11-09-10 15:00 | Manchester City | Blackburn Rovers | 1:1 |
| 11-09-10 15:00 | Newcastle United | FC Blackpool | 0:2 |
| 11-09-10 15:00 | West Bromwich Albion | Tottenham Hotspurs | 1:1 |
| 11-09-10 15:00 | West Ham United | FC Chelsea | 1:3 |
| 11-09-10 15:00 | Wigan Athletic | AFC Sunderland | 1:1 |
| 12-09-10 16:00 | Birmingham City | FC Liverpool | 0:0 |
| 13-09-10 20:00 | FC Stoke City | Aston Villa | 2:1 |