| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 20-11-10 12:45 | FC Arsenal | Tottenham Hotspurs | 2:3 |
| 20-11-10 15:00 | Birmingham City | FC Chelsea | 1:0 |
| 20-11-10 15:00 | FC Blackpool | Wolverhampton Wanderers | 2:1 |
| 20-11-10 15:00 | Bolton Wanderers | Newcastle United | 5:1 |
| 20-11-10 15:00 | Manchester United | Wigan Athletic | 2:0 |
| 20-11-10 15:00 | West Bromwich Albion | FC Stoke City | 0:3 |
| 20-11-10 17:30 | FC Liverpool | West Ham United | 3:0 |
| 21-11-10 13:30 | Blackburn Rovers | Aston Villa | 2:0 |
| 21-11-10 16:00 | FC Fulham | Manchester City | 1:4 |
| 22-11-10 20:00 | AFC Sunderland | FC Everton | 2:2 |