| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 18-05-21 18:00 | FC Southampton | Leeds United | 0:2 |
| 18-05-21 18:00 | Manchester United | FC Fulham | 1:1 |
| 18-05-21 19:00 | Brighton and Hove Albion | Manchester City | 3:2 |
| 18-05-21 20:15 | FC Chelsea | Leicester City | 2:1 |
| 19-05-21 18:00 | Newcastle United | Sheffield United | 1:0 |
| 19-05-21 18:00 | Tottenham Hotspurs | Aston Villa | 1:2 |
| 19-05-21 18:00 | FC Everton | Wolverhampton Wanderers | 1:0 |
| 19-05-21 19:00 | Crystal Palace | FC Arsenal | 1:3 |
| 19-05-21 20:15 | FC Burnley | FC Liverpool | 0:3 |
| 19-05-21 20:15 | West Bromwich Albion | West Ham United | 1:3 |