| Eastern Conference | Jo | Pts | Golos | Dif | V | E | D | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 16 | 44 | 45:12 | 33 | 14 | 2 | 0 |
| 2. | New England Revolution | 16 | 35 | 30:18 | 12 | 11 | 2 | 3 |
| 3. | Charlotte FC | 16 | 31 | 33:16 | 17 | 9 | 4 | 3 |
| 4. | Orlando City | 16 | 30 | 32:22 | 10 | 9 | 3 | 4 |
| 5. | Chicago Fire | 16 | 29 | 30:21 | 9 | 9 | 2 | 5 |
| 6. | Cincinnati FC | 15 | 27 | 38:30 | 8 | 8 | 3 | 4 |
| 7. | Toronto FC | 17 | 27 | 36:33 | 3 | 6 | 9 | 2 |
| 8. | Inter Miami CF | 16 | 26 | 43:28 | 15 | 6 | 8 | 2 |
| 9. | Philadelphia Union | 16 | 26 | 28:18 | 10 | 7 | 5 | 4 |
| 10. | Columbus Crew | 16 | 26 | 26:19 | 7 | 8 | 2 | 6 |
| 11. | New York Red Bulls | 16 | 21 | 24:29 | -5 | 6 | 3 | 7 |
| 12. | New York City FC | 16 | 20 | 29:23 | 6 | 5 | 5 | 6 |
| 13. | DC United | 16 | 20 | 20:28 | -8 | 5 | 5 | 6 |
| 14. | CF Montreal | 16 | 17 | 19:23 | -4 | 4 | 5 | 7 |
| 15. | Atlanta United FC | 16 | 14 | 23:32 | -9 | 4 | 2 | 10 |
| Western Conference | Jo | Pts | Golos | Dif | V | E | D | |
|---|---|---|---|---|---|---|---|---|
| 1. | Colorado Rapids | 16 | 33 | 29:15 | 14 | 10 | 3 | 3 |
| 2. | Vancouver Whitecaps | 16 | 32 | 39:15 | 24 | 10 | 2 | 4 |
| 3. | Los Angeles FC | 16 | 31 | 31:15 | 16 | 9 | 4 | 3 |
| 4. | St. Louis City SC | 16 | 31 | 36:22 | 14 | 9 | 4 | 3 |
| 5. | Real Salt Lake | 16 | 30 | 31:21 | 10 | 9 | 3 | 4 |
| 6. | FC Dallas | 16 | 29 | 29:22 | 7 | 8 | 5 | 3 |
| 7. | Houston Dynamo | 16 | 29 | 19:14 | 5 | 8 | 5 | 3 |
| 8. | Portland Timbers | 16 | 28 | 34:27 | 7 | 8 | 4 | 4 |
| 9. | Seattle Sounders | 16 | 25 | 24:22 | 2 | 7 | 4 | 5 |
| 10. | Los Angeles Galaxy | 16 | 24 | 22:20 | 2 | 6 | 6 | 4 |
| 11. | San Diego FC | 16 | 23 | 37:29 | 8 | 6 | 5 | 5 |
| 12. | San Jose Earthquakes | 16 | 23 | 28:25 | 3 | 6 | 5 | 5 |
| 13. | Minnesota United FC | 16 | 19 | 22:21 | 1 | 4 | 7 | 5 |
| 14. | Austin FC | 16 | 18 | 22:23 | -1 | 4 | 6 | 6 |
| 15. | Sporting Kansas City | 16 | 13 | 23:34 | -11 | 3 | 4 | 9 |