| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 16-05-24 0:30 | Philadelphia Union | New York City FC | 1:2 |
| 16-05-24 0:30 | Orlando City | Inter Miami CF | 0:0 |
| 16-05-24 0:30 | CF Montreal | Columbus Crew | 1:3 |
| 16-05-24 0:30 | Cincinnati FC | Atlanta United FC | 1:0 |
| 16-05-24 0:30 | DC United | New York Red Bulls | 1:4 |
| 16-05-24 1:30 | Chicago Fire | Charlotte FC | 0:1 |
| 16-05-24 1:30 | Nashville SC | Toronto FC | 2:0 |
| 16-05-24 1:30 | Minnesota United FC | Los Angeles Galaxy | 2:2 |
| 16-05-24 1:30 | St. Louis City SC | Los Angeles FC | 0:2 |
| 16-05-24 1:30 | Austin FC | Houston Dynamo | 1:0 |
| 16-05-24 2:30 | Colorado Rapids | Vancouver Whitecaps | 1:0 |
| 16-05-24 2:30 | Real Salt Lake | Seattle Sounders | 2:0 |
| 16-05-24 3:30 | Portland Timbers | San Jose Earthquakes | 4:2 |