| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 22-10-26 17:45 | Lech Poznan | AFC Sunderland | 1:1 |
| 22-10-26 17:45 | SK Sturm Graz | Olympique Marselha | 1:0 |
| 22-10-26 17:45 | Dínamo Zagreb | NEC Nijmwegen | 2:4 |
| 22-10-26 17:45 | Royale Union Saint-Gilloise | Hapoel Beer Sheva | 4:0 |
| 22-10-26 17:45 | Juventus Turim | Stade Rennes | 2:2 |
| 22-10-26 17:45 | FC Ararat-Armenia | AZ Alkmaar | 0:4 |
| 22-10-26 17:45 | OFI Crete | Bayer 04 Leverkusen | 0:2 |
| 22-10-26 17:45 | Ferencvaros Budapest | SCU Torreense | 4:1 |
| 22-10-26 20:00 | 1899 Hoffenheim | Olympique Lyon | 3:0 |
| 22-10-26 20:00 | Omonia Nicosia | Benfica | 1:4 |
| 22-10-26 20:00 | Jagiellonia Bialystok | RSC Anderlecht | 0:3 |
| 22-10-26 20:00 | NK Celje | FC Red Bull Salzburgo | 2:2 |
| 22-10-26 20:00 | AFC Bournemouth | AC Milão | 3:0 |
| 22-10-26 20:00 | Besiktas Istambul | Crystal Palace | 2:2 |
| 22-10-26 20:00 | Olympiakos Pireu | Sparta Praga | 1:0 |
| 22-10-26 20:00 | Celtic Glasgow | Celta Vigo | 1:2 |
| 22-10-26 20:00 | Viktoria Plzeň | Levski Sofia | 1:2 |
| 22-10-26 20:00 | Lillestroem SK | Real Sociedad | 0:6 |