| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 24-09-25 17:45 | PAOK Salónica | Maccabi Tel Avive | -:- |
| 24-09-25 17:45 | FC Midtjylland | SK Sturm Graz | -:- |
| 24-09-25 20:00 | Dínamo Zagreb | Fenerbahce Istambul | -:- |
| 24-09-25 20:00 | Estrela Vermelha Belgrado | Celtic Glasgow | -:- |
| 24-09-25 20:00 | Sporting Braga | Feyenoord Rotterdão | -:- |
| 24-09-25 20:00 | Real Betis Sevilla | Nottingham Forest | -:- |
| 24-09-25 20:00 | Malmö FF | PFC Ludogorets Razgrad | -:- |
| 24-09-25 20:00 | SC Friburgo | FC Basileia | -:- |
| 24-09-25 20:00 | OGC Nice | AS Roma | -:- |
| 25-09-25 17:45 | OSC Lille | Brann Bergen | -:- |
| 25-09-25 17:45 | Go Ahead Eagles Deventer | FCSB Bukarest | -:- |
| 25-09-25 20:00 | Glasgow Rangers | KRC Genk | -:- |
| 25-09-25 20:00 | Ferencvaros Budapest | Viktoria Plzeň | -:- |
| 25-09-25 20:00 | Young Boys Berna | Panathinaikos Atenas | -:- |
| 25-09-25 20:00 | Aston Villa | FC Bologna | -:- |
| 25-09-25 20:00 | FC Red Bull Salzburgo | FC Porto | -:- |
| 25-09-25 20:00 | FC Utrecht | Olympique Lyon | -:- |
| 25-09-25 20:00 | VfB Estugarda | Celta Vigo | -:- |