| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 12-09-25 19:30 | US Avellino | AC Monza | -:- |
| 13-09-25 14:00 | Cagliari Calcio | Parma Calcio 1913 | -:- |
| 13-09-25 14:00 | Juve Stabia | AC Reggiana 1919 | -:- |
| 13-09-25 14:00 | Modena FC | SSC Bari | -:- |
| 13-09-25 14:00 | Padova Calcio | Frosinone Calcio | -:- |
| 13-09-25 14:00 | Pescara Calcio | FC Venezia | -:- |
| 13-09-25 16:15 | US Catanzaro 1929 | Carrarese Calcio 1908 | -:- |
| 13-09-25 17:00 | Juventus Turim | Inter Milão | -:- |
| 13-09-25 18:30 | Sampdoria Génova | FC Cesena | -:- |
| 13-09-25 19:45 | AC Fiorentina | SSC Nápoles | -:- |
| 14-09-25 11:30 | AS Roma | FC Torino | -:- |
| 14-09-25 14:00 | Atalanta Bergamo | US Lecce | -:- |
| 14-09-25 14:00 | Pisa Sporting Club | Udinese Calcio | -:- |
| 14-09-25 14:00 | Virtus Entella | Mantova 1911 | -:- |
| 14-09-25 16:15 | FC Südtirol | Palermo FC | -:- |
| 14-09-25 17:00 | Sassuolo Calcio | Lazio Roma | -:- |
| 14-09-25 18:30 | FC Empoli | Spezia Calcio | -:- |
| 14-09-25 19:45 | AC Milão | FC Bologna | -:- |
| 15-09-25 17:30 | Hellas Verona | US Cremonese | -:- |
| 15-09-25 19:45 | Como Calcio | Genua CFC | -:- |