| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 07-12-25 16:15 | FC Empoli | Palermo FC | 1:3 |
| 07-12-25 18:30 | Sampdoria Génova | Carrarese Calcio 1908 | 3:2 |
| 08-12-25 11:30 | Modena FC | US Catanzaro 1929 | 1:2 |
| 08-12-25 14:00 | US Avellino | FC Venezia | 1:1 |
| 08-12-25 14:00 | Frosinone Calcio | Juve Stabia | 3:0 |
| 08-12-25 14:00 | Mantova 1911 | AC Reggiana 1919 | 0:1 |
| 08-12-25 14:00 | Padova Calcio | FC Cesena | 1:1 |
| 08-12-25 14:00 | AC Monza | FC Südtirol | 1:1 |
| 08-12-25 16:15 | SSC Bari | Pescara Calcio | 1:1 |
| 08-12-25 18:30 | Virtus Entella | Spezia Calcio | 0:1 |
| 12-12-25 19:45 | US Lecce | Pisa Sporting Club | 1:0 |
| 13-12-25 14:00 | FC Torino | US Cremonese | 1:0 |
| 13-12-25 17:00 | Parma Calcio 1913 | Lazio Roma | 0:1 |
| 13-12-25 19:45 | Atalanta Bergamo | Cagliari Calcio | 2:1 |
| 14-12-25 11:30 | AC Milão | Sassuolo Calcio | -:- |
| 14-12-25 14:00 | AC Fiorentina | Hellas Verona | -:- |
| 14-12-25 14:00 | Udinese Calcio | SSC Nápoles | -:- |
| 14-12-25 17:00 | Genua CFC | Inter Milão | -:- |
| 14-12-25 19:45 | FC Bologna | Juventus Turim | -:- |
| 15-12-25 19:45 | AS Roma | Como Calcio | -:- |