| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 09-08-25 19:30 | Virtus Entella | Ternana Calcio | 4:0 |
| 10-08-25 18:30 | Padova Calcio | Vicenza Calcio | 0:2 |
| 10-08-25 19:30 | US Avellino | Audace Cerignola | 0:1 |
| 10-08-25 19:30 | Pescara Calcio | Rimini FC | 1:0 |
| 15-08-25 17:00 | FC Empoli | AC Reggiana 1919 | 4:1a.pen./1:190m |
| 15-08-25 17:30 | Sassuolo Calcio | US Catanzaro 1929 | 1:0 |
| 15-08-25 19:45 | US Lecce | Juve Stabia | 2:0 |
| 15-08-25 20:15 | Genua CFC | Vicenza Calcio | 3:0 |
| 16-08-25 17:00 | FC Venezia | Mantova 1911 | 4:0 |
| 16-08-25 17:30 | Como Calcio | FC Südtirol | 3:1 |
| 16-08-25 19:45 | Cagliari Calcio | Virtus Entella | 6:5a.pen./1:190m |
| 16-08-25 20:15 | US Cremonese | Palermo FC | 4:5a.pen./0:090m |
| 17-08-25 17:00 | AC Monza | Frosinone Calcio | 0:1 |
| 17-08-25 17:30 | Parma Calcio 1913 | Pescara Calcio | 2:0 |
| 17-08-25 19:45 | FC Cesena | Pisa Sporting Club | 1:2a.pen./0:090m |
| 17-08-25 20:15 | AC Milão | SSC Bari | 2:0 |
| 18-08-25 17:00 | Audace Cerignola | Hellas Verona | 3:5a.pen./1:190m |
| 18-08-25 17:30 | Spezia Calcio | Sampdoria Génova | 5:3a.pen./1:190m |
| 18-08-25 19:45 | Udinese Calcio | Carrarese Calcio 1908 | 2:0 |
| 18-08-25 20:15 | FC Torino | Modena FC | 1:0 |
| 22-08-25 19:30 | Pescara Calcio | FC Cesena | 1:3 |
| 23-08-25 17:30 | Genua CFC | US Lecce | 0:0 |
| 23-08-25 17:30 | Sassuolo Calcio | SSC Nápoles | 0:2 |
| 23-08-25 18:00 | Virtus Entella | Juve Stabia | 1:1 |
| 23-08-25 18:00 | FC Empoli | Padova Calcio | 3:1 |
| 23-08-25 19:45 | AC Milão | US Cremonese | 1:2 |
| 23-08-25 19:45 | AS Roma | FC Bologna | 1:0 |
| 23-08-25 20:00 | AC Monza | Mantova 1911 | 1:0 |
| 23-08-25 20:00 | Palermo FC | AC Reggiana 1919 | 2:1 |
| 24-08-25 17:30 | Como Calcio | Lazio Roma | 2:0 |
| 24-08-25 17:30 | Cagliari Calcio | AC Fiorentina | 1:1 |
| 24-08-25 18:00 | Spezia Calcio | Carrarese Calcio 1908 | 0:2 |
| 24-08-25 18:00 | FC Venezia | SSC Bari | 2:1 |
| 24-08-25 19:45 | Atalanta Bergamo | Pisa Sporting Club | 1:1 |
| 24-08-25 19:45 | Juventus Turim | Parma Calcio 1913 | 2:0 |
| 24-08-25 20:00 | Frosinone Calcio | US Avellino | 2:0 |
| 24-08-25 20:00 | US Catanzaro 1929 | FC Südtirol | 1:1 |
| 25-08-25 17:30 | Udinese Calcio | Hellas Verona | 1:1 |
| 25-08-25 19:30 | Sampdoria Génova | Modena FC | 0:2 |
| 25-08-25 19:45 | Inter Milão | FC Torino | 5:0 |