| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 09-08-25 19:30 | Virtus Entella | Ternana Calcio | 4:0 |
| 10-08-25 18:30 | Padova Calcio | Vicenza Calcio | 0:2 |
| 10-08-25 19:30 | US Avellino | Audace Cerignola | 0:1 |
| 10-08-25 19:30 | Pescara Calcio | Rimini FC | 1:0 |
| 15-08-25 17:00 | FC Empoli | AC Reggiana 1919 | -:- |
| 15-08-25 17:30 | Sassuolo Calcio | US Catanzaro 1929 | -:- |
| 15-08-25 19:45 | US Lecce | Juve Stabia | -:- |
| 15-08-25 20:15 | Genua CFC | Vicenza Calcio | -:- |
| 16-08-25 17:00 | FC Venezia | Mantova 1911 | -:- |
| 16-08-25 17:30 | Como Calcio | FC Südtirol | -:- |
| 16-08-25 19:45 | Cagliari Calcio | Virtus Entella | -:- |
| 16-08-25 20:15 | US Cremonese | Palermo FC | -:- |
| 17-08-25 17:00 | AC Monza | Frosinone Calcio | -:- |
| 17-08-25 17:30 | Parma Calcio 1913 | Pescara Calcio | -:- |
| 17-08-25 19:45 | FC Cesena | Pisa Sporting Club | -:- |
| 17-08-25 20:15 | AC Milão | SSC Bari | -:- |
| 18-08-25 17:00 | Hellas Verona | Audace Cerignola | -:- |
| 18-08-25 17:30 | Spezia Calcio | Sampdoria Génova | -:- |
| 18-08-25 19:45 | Udinese Calcio | Carrarese Calcio 1908 | -:- |
| 18-08-25 20:15 | FC Torino | Modena FC | -:- |
| 22-08-25 19:30 | Pescara Calcio | FC Cesena | -:- |
| 23-08-25 17:30 | Genua CFC | US Lecce | -:- |
| 23-08-25 17:30 | Sassuolo Calcio | SSC Nápoles | -:- |
| 23-08-25 18:00 | Virtus Entella | Juve Stabia | -:- |
| 23-08-25 18:00 | FC Empoli | Padova Calcio | -:- |
| 23-08-25 19:45 | AC Milão | US Cremonese | -:- |
| 23-08-25 19:45 | AS Roma | FC Bologna | -:- |
| 23-08-25 20:00 | AC Monza | Mantova 1911 | -:- |
| 23-08-25 20:00 | Palermo FC | AC Reggiana 1919 | -:- |
| 24-08-25 17:30 | Como Calcio | Lazio Roma | -:- |
| 24-08-25 17:30 | Cagliari Calcio | AC Fiorentina | -:- |
| 24-08-25 18:00 | Spezia Calcio | Carrarese Calcio 1908 | -:- |
| 24-08-25 18:00 | FC Venezia | SSC Bari | -:- |
| 24-08-25 19:45 | Atalanta Bergamo | Pisa Sporting Club | -:- |
| 24-08-25 19:45 | Juventus Turim | Parma Calcio 1913 | -:- |
| 24-08-25 20:00 | Frosinone Calcio | US Avellino | -:- |
| 24-08-25 20:00 | US Catanzaro 1929 | FC Südtirol | -:- |
| 25-08-25 17:30 | Udinese Calcio | Hellas Verona | -:- |
| 25-08-25 19:30 | Sampdoria Génova | Modena FC | -:- |
| 25-08-25 19:45 | Inter Milão | FC Torino | -:- |