| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|
| 14-10-22 19:30 | 14-10-22 19:00 | FC Schalke 04 | 1899 Hoffenheim | 0:3 | 2 - 4 pontos |
| 15-10-22 14:30 | 15-10-22 14:00 | Eintracht Frankfurt | Bayer 04 Leverkusen | 5:1 | 2 - 4 pontos |
| 15-10-22 14:30 | 15-10-22 14:00 | VfB Estugarda | VfL Bochum | 4:1 | 2 - 4 pontos |
| 15-10-22 14:30 | 15-10-22 14:00 | VfL Wolfsburgo | Bor. Mönchengladbach | 2:2 | 2 - 4 pontos |
| 15-10-22 14:30 | 15-10-22 14:00 | Werder Bremen | FSV Mainz 05 | 0:2 | 2 - 4 pontos |
| 15-10-22 17:30 | 15-10-22 17:00 | RB Leipzig | Hertha BSC Berlim | 3:2 | 2 - 4 pontos |
| 16-10-22 14:30 | 16-10-22 14:00 | 1. FC Colónia | FC Augsburg | 3:2 | 2 - 4 pontos |
| 16-10-22 16:30 | 16-10-22 16:00 | 1. FC Union Berlim | Borussia Dortmund | 2:0 | 2 - 4 pontos |
| 16-10-22 18:30 | 16-10-22 18:00 | FC Bayern Munique | SC Friburgo | 5:0 | 2 - 4 pontos |
