| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 22-01-26 17:45 | Viktoria Plzeň | FC Porto | -:- |
| 22-01-26 17:45 | Young Boys Berna | Olympique Lyon | -:- |
| 22-01-26 17:45 | Feyenoord Rotterdão | SK Sturm Graz | -:- |
| 22-01-26 17:45 | SC Friburgo | Maccabi Tel Avive | -:- |
| 22-01-26 17:45 | PAOK Salónica | Real Betis Sevilla | -:- |
| 22-01-26 17:45 | FC Bologna | Celtic Glasgow | -:- |
| 22-01-26 17:45 | Malmö FF | Estrela Vermelha Belgrado | -:- |
| 22-01-26 17:45 | Fenerbahce Istambul | Aston Villa | -:- |
| 22-01-26 17:45 | Brann Bergen | FC Midtjylland | -:- |
| 22-01-26 20:00 | FC Utrecht | KRC Genk | -:- |
| 22-01-26 20:00 | Ferencvaros Budapest | Panathinaikos Atenas | -:- |
| 22-01-26 20:00 | OGC Nice | Go Ahead Eagles Deventer | -:- |
| 22-01-26 20:00 | Celta Vigo | OSC Lille | -:- |
| 22-01-26 20:00 | Sporting Braga | Nottingham Forest | -:- |
| 22-01-26 20:00 | FC Red Bull Salzburgo | FC Basileia | -:- |
| 22-01-26 20:00 | Dínamo Zagreb | FCSB Bukarest | -:- |
| 22-01-26 20:00 | Glasgow Rangers | PFC Ludogorets Razgrad | -:- |
| 22-01-26 20:00 | AS Roma | VfB Estugarda | -:- |