| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 11-12-25 17:45 | FC Midtjylland | KRC Genk | -:- |
| 11-12-25 17:45 | PFC Ludogorets Razgrad | PAOK Salónica | -:- |
| 11-12-25 17:45 | FC Utrecht | Nottingham Forest | -:- |
| 11-12-25 17:45 | Ferencvaros Budapest | Glasgow Rangers | -:- |
| 11-12-25 17:45 | Young Boys Berna | OSC Lille | -:- |
| 11-12-25 17:45 | VfB Estugarda | Maccabi Tel Avive | -:- |
| 11-12-25 17:45 | Dínamo Zagreb | Real Betis Sevilla | -:- |
| 11-12-25 17:45 | SK Sturm Graz | Estrela Vermelha Belgrado | -:- |
| 11-12-25 17:45 | OGC Nice | Sporting Braga | -:- |
| 11-12-25 20:00 | FC Porto | Malmö FF | -:- |
| 11-12-25 20:00 | FC Basileia | Aston Villa | -:- |
| 11-12-25 20:00 | Olympique Lyon | Go Ahead Eagles Deventer | -:- |
| 11-12-25 20:00 | Panathinaikos Atenas | Viktoria Plzeň | -:- |
| 11-12-25 20:00 | SC Friburgo | FC Red Bull Salzburgo | -:- |
| 11-12-25 20:00 | FCSB Bukarest | Feyenoord Rotterdão | -:- |
| 11-12-25 20:00 | Celta Vigo | FC Bologna | -:- |
| 11-12-25 20:00 | Celtic Glasgow | AS Roma | -:- |
| 11-12-25 20:00 | Brann Bergen | Fenerbahce Istambul | -:- |