| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 27-11-25 17:45 | PAOK Salónica | Brann Bergen | -:- |
| 27-11-25 17:45 | PFC Ludogorets Razgrad | Celta Vigo | -:- |
| 27-11-25 17:45 | Feyenoord Rotterdão | Celtic Glasgow | -:- |
| 27-11-25 17:45 | OSC Lille | Dínamo Zagreb | -:- |
| 27-11-25 17:45 | Aston Villa | Young Boys Berna | -:- |
| 27-11-25 17:45 | FC Porto | OGC Nice | -:- |
| 27-11-25 17:45 | Fenerbahce Istambul | Ferencvaros Budapest | -:- |
| 27-11-25 17:45 | Viktoria Plzeň | SC Friburgo | -:- |
| 27-11-25 17:45 | AS Roma | FC Midtjylland | -:- |
| 27-11-25 20:00 | KRC Genk | FC Basileia | -:- |
| 27-11-25 20:00 | Nottingham Forest | Malmö FF | -:- |
| 27-11-25 20:00 | Go Ahead Eagles Deventer | VfB Estugarda | -:- |
| 27-11-25 20:00 | Panathinaikos Atenas | SK Sturm Graz | -:- |
| 27-11-25 20:00 | FC Bologna | FC Red Bull Salzburgo | -:- |
| 27-11-25 20:00 | Maccabi Tel Avive | Olympique Lyon | -:- |
| 27-11-25 20:00 | Estrela Vermelha Belgrado | FCSB Bukarest | -:- |
| 27-11-25 20:00 | Glasgow Rangers | Sporting Braga | -:- |
| 27-11-25 20:00 | Real Betis Sevilla | FC Utrecht | -:- |