| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 04-11-25 17:45 | Slavia Praga | FC Arsenal | 0:3 |
| 04-11-25 17:45 | SSC Nápoles | Eintracht Frankfurt | 0:0 |
| 04-11-25 20:00 | Olympiakos Pireu | PSV Eindhoven | 1:1 |
| 04-11-25 20:00 | FC Liverpool | Real Madrid | 1:0 |
| 04-11-25 20:00 | Juventus Turim | Sporting | 1:1 |
| 04-11-25 20:00 | Paris St. Germain | FC Bayern Munique | 1:2 |
| 04-11-25 20:00 | Atlético Madrid | Royale Union Saint-Gilloise | 3:1 |
| 04-11-25 20:00 | Tottenham Hotspurs | FC Copenhaga | 4:0 |
| 04-11-25 20:00 | FK Bodö/Glimt | AS Mónaco | 0:1 |
| 05-11-25 17:45 | Qarabag | FC Chelsea | 2:2 |
| 05-11-25 17:45 | Pafos FC | FC Villarreal | 1:0 |
| 05-11-25 20:00 | Manchester City | Borussia Dortmund | 4:1 |
| 05-11-25 20:00 | Benfica | Bayer 04 Leverkusen | 0:1 |
| 05-11-25 20:00 | Olympique Marselha | Atalanta Bergamo | 0:1 |
| 05-11-25 20:00 | Inter Milão | Kairat Almaty | 2:1 |
| 05-11-25 20:00 | FC Brugges | FC Barcelona | 3:3 |
| 05-11-25 20:00 | Ajax Amsterdão | Galatasaray Istambul | 0:3 |
| 05-11-25 20:00 | Newcastle United | Athletic Bilbao | 2:0 |