| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 30-09-25 17:45 | Atalanta Bergamo | FC Brugges | 2:1 |
| 30-09-25 17:45 | Kairat Almaty | Real Madrid | 0:5 |
| 30-09-25 20:00 | Pafos FC | FC Bayern Munique | 1:5 |
| 30-09-25 20:00 | FC Chelsea | Benfica | 1:0 |
| 30-09-25 20:00 | Inter Milão | Slavia Praga | 3:0 |
| 30-09-25 20:00 | Galatasaray Istambul | FC Liverpool | 1:0 |
| 30-09-25 20:00 | Atlético Madrid | Eintracht Frankfurt | 5:1 |
| 30-09-25 20:00 | Olympique Marselha | Ajax Amsterdão | 4:0 |
| 30-09-25 20:00 | FK Bodö/Glimt | Tottenham Hotspurs | 2:2 |
| 01-10-25 17:45 | Qarabag | FC Copenhaga | 2:0 |
| 01-10-25 17:45 | Royale Union Saint-Gilloise | Newcastle United | 0:4 |
| 01-10-25 20:00 | Bayer 04 Leverkusen | PSV Eindhoven | 1:1 |
| 01-10-25 20:00 | Borussia Dortmund | Athletic Bilbao | 4:1 |
| 01-10-25 20:00 | FC Barcelona | Paris St. Germain | 1:2 |
| 01-10-25 20:00 | AS Mónaco | Manchester City | 2:2 |
| 01-10-25 20:00 | FC Arsenal | Olympiakos Pireu | 2:0 |
| 01-10-25 20:00 | FC Villarreal | Juventus Turim | 2:2 |
| 01-10-25 20:00 | SSC Nápoles | Sporting | 2:1 |