| 11-12-19 18:00 | UD Logrones | Marino Luanco | 2:1 |
| 17-12-19 14:30 | CD Lealtad de Villaviciosa | FC Cádiz | 0:1 |
| 17-12-19 15:00 | FC Coruxo | CD Mirandés | 4:5a.p. |
| 17-12-19 18:00 | SD Logrones | SD Eibar | 0:5 |
| 17-12-19 18:00 | Illueca CF | Deportivo La Coruña | 0:2 |
| 17-12-19 18:00 | Real Jaen | Deportivo Alavés | 3:1 |
| 17-12-19 18:00 | CE L'Hospitalet | FC Granada | 2:3a.p. |
| 17-12-19 18:30 | Marbella FC | CD Guijuelo | 2:1 |
| 17-12-19 18:30 | UP Langreo | CD Ebro | 2:3 |
| 17-12-19 19:00 | CD Castellón | UD Las Palmas | 0:2 |
| 17-12-19 19:00 | FC Pena Sport | CF Fuenlabrada | 0:1a.p. |
| 17-12-19 19:00 | CP Cacereno | AD Alcorcón | 1:0 |
| 17-12-19 19:00 | UD Socuellamos | Real Zaragoza | 0:1 |
| 17-12-19 19:00 | Club Portugalete | UD Extremadura | 1:0 |
| 17-12-19 19:15 | Sociedad Deportivo Tarazona | Rayo Vallecano | 0:1a.p. |
| 17-12-19 19:30 | UM Escobedo | FC Málaga | 2:0 |
| 17-12-19 19:30 | Zamora CF | Sporting Gijón | 2:1 |
| 17-12-19 19:30 | Unionistas CF | Atletico Baleares | 1:0 |
| 17-12-19 19:30 | Gimnastica Segoviana | FC Elche | 0:2 |
| 17-12-19 19:30 | CD Mensajero | CD Teneriffa | 0:3 |
| 17-12-19 19:45 | CF Hercules | Recreativo Huelva | 0:1 |
| 17-12-19 20:00 | FC Cartagena | SD Leioa | 4:1 |
| 17-12-19 20:00 | Andorra CF | CD Leganés | 6:7a.pen. |
| 17-12-19 20:00 | Real Murcia | Racing Santander | 1:0 |
| 17-12-19 20:00 | CF Intercity | Athletic Bilbao | 0:3 |
| 17-12-19 20:00 | AD Ceuta | CD Numancia | 4:3a.pen. |
| 18-12-19 16:30 | San Sebastian Reyes | Cordóba CF | 2:0 |
| 18-12-19 17:00 | CF Badalona | Real Oviedo | 3:1 |
| 18-12-19 17:00 | UD Melilla | UCAM Múrcia | 1:2 |
| 18-12-19 17:00 | CD El Alamo | RCD Mallorca | 0:1 |
| 18-12-19 17:00 | Comillas CF | FC Villarreal | 0:5 |
| 18-12-19 17:00 | CD Tudelano | Albacete Balompie | 0:1 |
| 18-12-19 17:00 | Bergantinos CF | FC Sevilla | 0:1 |
| 18-12-19 17:00 | Estrella Grana El Palmar CF | FC Getafe | 1:2 |
| 18-12-19 17:00 | Tolosa CF | Real Valladolid | 0:3 |
| 18-12-19 19:00 | Sestao River Club | CD Lugo | 7:6a.pen. |
| 18-12-19 19:15 | Barakaldo CF | Villarrubia CF | 5:3a.pen. |
| 19-12-19 18:00 | CD Pena Azagresa | Celta Vigo | 0:2 |
| 19-12-19 18:00 | Pd Santa Eulalia | SD Ponferradina | 0:1a.p. |
| 19-12-19 18:00 | Cultural y Deportiva Leonesa | Las Rozas CF | 3:0 |
| 19-12-19 18:00 | SD Amorebieta | CD Badajoz | 0:1 |
| 19-12-19 18:00 | Club Lleida Esportiu | Espanyol Barcelona | 0:2 |
| 19-12-19 18:00 | Melilla CD | UD Levante | 0:5 |
| 19-12-19 18:00 | CA Antoniano | Real Betis Sevilla | 0:4 |
| 19-12-19 19:00 | UE Llagostera | Club Haro Deportivo | 0:1a.p. |
| 19-12-19 19:00 | CF Rayo Majadahonda | Racing Club de Ferrol | 1:0 |
| 19-12-19 19:30 | UE Cornella | Orihuela CF | 4:5a.pen. |
| 19-12-19 19:30 | CD Laredo | SD Huesca | 0:1 |
| 19-12-19 19:30 | Gimnástic de Tarragona | Olot | 3:1a.p. |
| 19-12-19 19:30 | UD Tamaraceite | UD Almeria | 3:2a.p. |
| Cancelado | Mérida AD | CF La Nucia | -:- |
| 19-12-19 20:00 | CD Becerril | Real Sociedad | 0:8 |
| 19-12-19 20:00 | Linares Deportivo | FC Girona | 1:2 |
| 19-12-19 20:00 | Lorca Deportiva CF | CA Osasuna | 0:3 |
| 08-01-20 19:30 | CF Pontevedra | UD Ibiza Eivissa | 0:2 |
