| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 19-03-26 17:45 | AEK Atenas | NK Celje | 0:2 |
| 19-03-26 17:45 | KS Rakow Czestochowa | AC Fiorentina | 1:2 |
| 19-03-26 17:45 | FSV Mainz 05 | Sigma Olomouc | 2:0 |
| 19-03-26 17:45 | AEK Larnaca | Crystal Palace | 1:2a.p. |
| 19-03-26 20:00 | Racing Club Estrasburgo | HNK Rijeka | 1:1 |
| 19-03-26 20:00 | Sparta Praga | AZ Alkmaar | 0:4 |
| 19-03-26 20:00 | Rayo Vallecano | Samsunspor | 0:1 |
| 19-03-26 20:00 | Shaktiar Donetsk | Lech Poznan | 1:2 |