Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 02-12-25 17:45 | 02-12-25 17:45 | Elverum Håndball | Fram | 38:24 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | Fredericia HK | IK Sävehof | 29:33 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | HC Kriens-Luzern | Porto | 25:44 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | IFK Kristianstad | Sesvete | 28:27 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | Potaissa Turda | St. Raphael | 25:34 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | Presov | TSV Hanôver-Burgdorf | 29:37 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | SG Flensburg-Handewitt | CD Bidasoa Irún | 38:35 | 2 - 17 pontos |
| 02-12-25 17:45 | 02-12-25 17:45 | Vardar 1961 | Toulouse | 37:35 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | Benfica | MT Melsungen | 26:30 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | BM Granollers | Minaur Baia Mare | 29:28 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | BSV Bern Muri | Ostrow Wielkopolski | 28:28 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | Kadetten Schaffhausen | Partizan | 32:19 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | Karlskrona | Ferencváros | 31:32 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | RK Našice | Ademar León | 29:28 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | Slovan | Skanderborg AGF | 30:37 | 2 - 17 pontos |
| 02-12-25 19:45 | 02-12-25 19:45 | THW Kiel | Montpellier Handball | 27:18 | 2 - 17 pontos |