Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 18-11-25 17:45 | 18-11-25 17:45 | Ferencváros | MT Melsungen | 25:28 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | IK Sävehof | TSV Hanôver-Burgdorf | 28:30 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | Kadetten Schaffhausen | RK Našice | 31:32 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | Montpellier Handball | Ostrow Wielkopolski | 37:26 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | Skanderborg AGF | Minaur Baia Mare | 39:26 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | THW Kiel | BSV Bern Muri | 37:27 | 2 - 17 pontos |
| 18-11-25 17:45 | 18-11-25 17:45 | Vardar 1961 | IFK Kristianstad | 35:30 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Ademar León | Partizan | 29:22 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Benfica | Karlskrona | 36:33 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | BM Granollers | Slovan | 27:35 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | CD Bidasoa Irún | St. Raphael | 33:25 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Fram | HC Kriens-Luzern | 31:35 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Fredericia HK | Presov | 38:30 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Porto | Elverum Håndball | 29:31 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | SG Flensburg-Handewitt | Potaissa Turda | 46:28 | 2 - 17 pontos |
| 18-11-25 19:45 | 18-11-25 19:45 | Toulouse | Sesvete | 32:37 | 2 - 17 pontos |