Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 11-11-25 16:00 | 11-11-25 16:00 | Minaur Baia Mare | Skanderborg AGF | 27:45 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Elverum Håndball | Porto | 25:29 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | HC Kriens-Luzern | Fram | 40:25 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | IFK Kristianstad | Vardar 1961 | 32:31 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | MT Melsungen | Ferencváros | 33:27 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Ostrow Wielkopolski | Montpellier Handball | 25:38 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Partizan | Ademar León | 25:18 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Potaissa Turda | SG Flensburg-Handewitt | 26:33 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Presov | Fredericia HK | 27:34 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Sesvete | Toulouse | 32:31 | 2 - 17 pontos |
| 11-11-25 17:45 | 11-11-25 17:45 | Slovan | BM Granollers | 29:34 | 2 - 17 pontos |
| 11-11-25 19:45 | 11-11-25 19:45 | BSV Bern Muri | THW Kiel | 27:35 | 2 - 17 pontos |
| 11-11-25 19:45 | 11-11-25 19:45 | Karlskrona | Benfica | 32:34 | 2 - 17 pontos |
| 11-11-25 19:45 | 11-11-25 19:45 | RK Našice | Kadetten Schaffhausen | 29:30 | 2 - 17 pontos |
| 11-11-25 19:45 | 11-11-25 19:45 | St. Raphael | CD Bidasoa Irún | 35:32 | 2 - 17 pontos |
| 11-11-25 19:45 | 11-11-25 19:45 | TSV Hanôver-Burgdorf | IK Sävehof | 27:25 | 2 - 17 pontos |