Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 21-10-25 17:45 | 21-10-25 17:45 | BSV Bern Muri | Montpellier Handball | 31:37 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | IK Sävehof | Fredericia HK | 29:29 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | Minaur Baia Mare | BM Granollers | 24:24 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | Partizan | Kadetten Schaffhausen | 29:26 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | Sesvete | IFK Kristianstad | 32:32 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | Skanderborg AGF | Slovan | 34:30 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | THW Kiel | Ostrow Wielkopolski | 34:21 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | Toulouse | Vardar 1961 | 26:28 | 2 - 17 pontos |
| 21-10-25 17:45 | 21-10-25 17:45 | TSV Hanôver-Burgdorf | Presov | 40:28 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | Ademar León | RK Našice | 28:28 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | Benfica | Ferencváros | 38:25 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | CD Bidasoa Irún | SG Flensburg-Handewitt | 32:33 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | Fram | Elverum Håndball | 29:35 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | Karlskrona | MT Melsungen | 25:26 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | Porto | HC Kriens-Luzern | 44:31 | 2 - 17 pontos |
| 21-10-25 19:45 | 21-10-25 19:45 | St. Raphael | Potaissa Turda | 42:24 | 2 - 17 pontos |