Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 01-10-21 20:00 | 01-10-21 20:00 | RC Lens | Stade Reims | 2:0 | 2 - 5 pontos |
| 02-10-21 16:00 | 02-10-21 16:00 | HSC Montpellier | Racing Club Estrasburgo | 1:1 | 2 - 5 pontos |
| 02-10-21 20:00 | 02-10-21 20:00 | OGC Nice | Stade Brest 29 | 2:1 | 2 - 5 pontos |
| 03-10-21 12:00 | 03-10-21 12:00 | Stade Rennes | Paris St. Germain | 2:0 | 2 - 5 pontos |
| 03-10-21 14:00 | 03-10-21 14:00 | FC Lorient | Clermont Foot | 1:1 | 2 - 5 pontos |
| 03-10-21 14:00 | 03-10-21 14:00 | AS Mónaco | Girondins Bordeaux | 3:0 | 2 - 5 pontos |
| 03-10-21 14:00 | 03-10-21 14:00 | FC Nantes | ES Troyes AC | 2:0 | 2 - 5 pontos |
| 03-10-21 14:00 | 03-10-21 14:00 | SCO Angers | FC Metz | 3:2 | 2 - 5 pontos |
| 03-10-21 16:05 | 03-10-21 16:05 | OSC Lille | Olympique Marselha | 2:0 | 2 - 5 pontos |
| 03-10-21 19:45 | 03-10-21 19:45 | AS St. Etienne | Olympique Lyon | 1:1 | 2 - 5 pontos |