Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 15-10-21 20:00 | 15-10-21 20:00 | Paris St. Germain | SCO Angers | 2:1 | 2 - 5 pontos |
| 16-10-21 16:00 | 16-10-21 16:00 | Clermont Foot | OSC Lille | 1:0 | 2 - 5 pontos |
| 16-10-21 20:00 | 16-10-21 20:00 | Olympique Lyon | AS Mónaco | 2:0 | 2 - 5 pontos |
| 17-10-21 12:00 | 17-10-21 12:00 | ES Troyes AC | OGC Nice | 1:0 | 2 - 5 pontos |
| 17-10-21 14:00 | 17-10-21 14:00 | Racing Club Estrasburgo | AS St. Etienne | 5:1 | 2 - 5 pontos |
| 17-10-21 14:00 | 17-10-21 14:00 | Girondins Bordeaux | FC Nantes | 1:1 | 2 - 5 pontos |
| 17-10-21 14:00 | 17-10-21 14:00 | Stade Brest 29 | Stade Reims | 1:1 | 2 - 5 pontos |
| 17-10-21 14:00 | 17-10-21 14:00 | FC Metz | Stade Rennes | 0:3 | 2 - 5 pontos |
| 17-10-21 16:05 | 17-10-21 16:05 | HSC Montpellier | RC Lens | 1:0 | 2 - 5 pontos |
| 17-10-21 19:45 | 17-10-21 19:45 | Olympique Marselha | FC Lorient | 4:1 | 2 - 5 pontos |