Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 19-08-22 17:30 | 19-08-22 17:30 | 1. FC Magdeburg | Hannover 96 | 0:4 | 2 - 5 pontos |
| 19-08-22 17:30 | 19-08-22 17:30 | Hamburgo SV | SV Darmstadt 98 | 1:2 | 2 - 5 pontos |
| 20-08-22 12:00 | 20-08-22 12:00 | SV Sandhausen | 1. FC Nuremberga | 1:2 | 2 - 5 pontos |
| 20-08-22 12:00 | 20-08-22 12:00 | SC Paderborn 07 | Holstein Kiel | 7:2 | 2 - 5 pontos |
| 20-08-22 12:00 | 20-08-22 12:00 | Jahn Regensburg | Karlsruher SC | 0:6 | 2 - 5 pontos |
| 20-08-22 19:30 | 20-08-22 19:30 | Eintracht Braunschweig | Fortuna Düsseldorf | 2:2 | 2 - 5 pontos |
| 21-08-22 12:30 | 21-08-22 12:30 | SpVgg Greuther Fürth | 1. FC Kaiserslautern | 1:3 | 2 - 5 pontos |
| 21-08-22 12:30 | 21-08-22 12:30 | 1. FC Heidenheim 1846 | Arminia Bielefeld | 1:1 | 2 - 5 pontos |
| 21-08-22 12:30 | 21-08-22 12:30 | FC Hansa Rostock | FC St. Pauli | 2:0 | 2 - 5 pontos |