Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 05-08-22 17:30 | 05-08-22 17:30 | SV Sandhausen | Fortuna Düsseldorf | 1:0 | 2 - 5 pontos |
| 05-08-22 17:30 | 05-08-22 17:30 | SpVgg Greuther Fürth | Karlsruher SC | 1:1 | 2 - 5 pontos |
| 06-08-22 12:00 | 06-08-22 12:00 | SC Paderborn 07 | Hannover 96 | 4:2 | 2 - 5 pontos |
| 06-08-22 12:00 | 06-08-22 12:00 | Hamburgo SV | 1. FC Heidenheim 1846 | 1:0 | 2 - 5 pontos |
| 06-08-22 12:00 | 06-08-22 12:00 | Jahn Regensburg | 1. FC Nuremberga | 0:0 | 2 - 5 pontos |
| 06-08-22 19:30 | 06-08-22 19:30 | FC Hansa Rostock | Arminia Bielefeld | 2:1 | 2 - 5 pontos |
| 07-08-22 12:30 | 07-08-22 12:30 | 1. FC Kaiserslautern | FC St. Pauli | 2:1 | 2 - 5 pontos |
| 07-08-22 12:30 | 07-08-22 12:30 | Eintracht Braunschweig | SV Darmstadt 98 | 0:1 | 2 - 5 pontos |
| 07-08-22 12:30 | 07-08-22 12:30 | 1. FC Magdeburg | Holstein Kiel | 1:2 | 2 - 5 pontos |