Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 04-02-22 19:30 | 04-02-22 19:30 | Hertha BSC Berlim | VfL Bochum | 1:1 | 3 - 4 - 6 |
| 05-02-22 14:30 | 05-02-22 14:30 | VfB Estugarda | Eintracht Frankfurt | 2:3 | 5 - 4 - 4 |
| 05-02-22 14:30 | 05-02-22 14:30 | 1. FC Colónia | SC Friburgo | 1:0 | 4 - 5 - 4 |
| 05-02-22 14:30 | 05-02-22 14:30 | Arminia Bielefeld | Bor. Mönchengladbach | 1:1 | 6 - 5 - 3 |
| 05-02-22 14:30 | 05-02-22 14:30 | FC Augsburg | 1. FC Union Berlim | 2:0 | 6 - 4 - 3 |
| 05-02-22 14:30 | 05-02-22 14:30 | FSV Mainz 05 | 1899 Hoffenheim | 2:0 | 3 - 4 - 6 |
| 05-02-22 17:30 | 05-02-22 17:30 | FC Bayern Munique | RB Leipzig | 3:2 | 3 - 6 - 6 |
| 06-02-22 14:30 | 06-02-22 14:30 | Borussia Dortmund | Bayer 04 Leverkusen | 2:5 | 3 - 5 - 6 |
| 06-02-22 16:30 | 06-02-22 16:30 | VfL Wolfsburgo | SpVgg Greuther Fürth | 4:1 | 3 - 5 - 6 |